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HOW AND WHERE TO BUY VICODIN, LORTAB, NORCO (HYDROCODONE WITH ACETAMINOPHEN / PARACETAMOL) 10MG/325MG TABLETS OR CAPSULES ONLINE:

VICODIN, VICODIN ES, VICODIN HP (HYDROCODONE/ACETAMINOPHEN) TABLETS: WITHDRAWAL

Neonatal Opioid Withdrawal Syndrome

Prolonged use of Vicodin (Hydrocodone Bitartrate with Acetaminophen) tablets during pregnancy can result in withdrawal in the neonate. Neonatal opioid withdrawal syndrome, unlike opioid withdrawal syndrome in adults, may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. Observe newborns for signs of neonatal opioid withdrawal syndrome and manage accordingly. Advise pregnant women using opioids for a prolonged period of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available.

Withdrawal

Avoid the use of mixed agonist/antagonist (e.g, pentazocine, nalbuphine, and butorphanol) or partial agonist (e.g., buprenorphine) analgesics in patients who are receiving a full opioid agonist analgesic, including Vicodin, Vicodin ES, Vicodin HP. In these patients, mixed agonist/antagonist and partial analgesics may reduce the analgesic effect and/or precipitate withdrawal symptoms.

When discontinuing Vicodin (Hydrocodone, Paracetamol), gradually taper the dosage. Do not abruptly discontinue this medication in patients who have been using this drug around the clock for more than 5 days.

Concomitant use of hydrocodone bitartrate and acetaminophen tablets with CYP3A4 inducers or discontinuation of an CYP3A4 inhibitor could decrease hydrocodone plasma concentrations, decrease opioid efficacy or, possibly, lead to a withdrawal syndrome in a patient who had developed physical dependence to hydrocodone. When using Vicodin (Hydrocodone Bitartrate and Acetaminophen) with CYP3A4 inducers or discontinuing CYP3A4 inhibitors, follow patients at frequent intervals and consider increasing the opioid dosage if needed to maintain adequate analgesia or if symptoms of opioid withdrawal occur.

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